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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000614

Entrez Gene ID

864

Official Gene Symbol

RUNX3

Synonyms

AML2|CBFA3|FLJ34510|MGC16070|PEBP2aC

Gene name

runt-related transcription factor 3

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36

Known cancer genes

Yes

Protein products

Runt-related transcription factor 3

Core binding factor alpha 3 subunit

Runt-related transcription factor 3

Related liver disease name

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:10473
MIM:600210
Ensembl:ENSG00000020633
HPRD:02565
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0006366

transcription from RNA polymerase II promoter

GO:0006468

protein phosphorylation

GO:0006917

induction of apoptosis

GO:0008283

cell proliferation

GO:0045786

negative regulation of cell cycle

GO:0050680

negative regulation of epithelial cell proliferation