HuLG000628

Entrez Gene ID

889

Official Gene Symbol

KRIT1

Synonyms

CAM|CCM1

Gene name

KRIT1, ankyrin repeat containing

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q21.2

Known cancer genes

Yes

Protein products

Cerebral cavernous malformations 1

Uncharacterized protein

Krev interaction trapped protein 1

Related liver disease name

Viral hepatitis

Database cross reference

HGNC:1573
MIM:604214
Ensembl:ENSG00000001631
HPRD:05020
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

GO annotation

GO:0001937

negative regulation of endothelial cell proliferation

GO:0005083

small GTPase regulator activity

GO:0005515

protein binding

GO:0005856

cytoskeleton

GO:0005911

cell-cell junction

GO:0007264

small GTPase mediated signal transduction

GO:0010596

negative regulation of endothelial cell migration

GO:0016020

membrane

GO:0016525

negative regulation of angiogenesis

GO:0032092

positive regulation of protein binding

GO:0043234

protein complex

GO:0045454

cell redox homeostasis

GO:2000114

regulation of establishment of cell polarity

GO:2000352

negative regulation of endothelial cell apoptosis