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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000634

Entrez Gene ID

898

Official Gene Symbol

CCNE1

Synonyms

CCNE

Gene name

cyclin E1

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q12

Known cancer genes

Yes

Protein products

Uncharacterized protein

G1/S-specific cyclin-E1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1589
MIM:123837
Ensembl:ENSG00000105173
HPRD:00455
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000079

regulation of cyclin-dependent protein kinase activity

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000083

regulation of transcription involved in G1/S phase of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0000307

cyclin-dependent protein kinase holoenzyme complex

GO:0001547

antral ovarian follicle growth

GO:0001889

liver development

GO:0003713

transcription coactivator activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005813

centrosome

GO:0005829

cytosol

GO:0006270

DNA-dependent DNA replication initiation

GO:0006468

protein phosphorylation

GO:0010243

response to organic nitrogen

GO:0014074

response to purine-containing compound

GO:0016055

Wnt receptor signaling pathway

GO:0016301

kinase activity

GO:0016538

cyclin-dependent protein kinase regulator activity

GO:0019901

protein kinase binding

GO:0030521

androgen receptor signaling pathway

GO:0031100

organ regeneration

GO:0031670

cellular response to nutrient

GO:0032355

response to estradiol stimulus

GO:0032403

protein complex binding

GO:0032570

response to progesterone stimulus

GO:0033197

response to vitamin E

GO:0034097

response to cytokine stimulus

GO:0042493

response to drug

GO:0045471

response to ethanol

GO:0045597

positive regulation of cell differentiation

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0050681

androgen receptor binding

GO:0051301

cell division

GO:0051412

response to corticosterone stimulus

GO:0051597

response to methylmercury