HuLG000651

Entrez Gene ID

919

Official Gene Symbol

CD247

Synonyms

CD3NZETA|CD3H|CD3Q|CD3Z|T3Z|TCRZ

Gene name

CD247 molecule

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q22-q23

Known cancer genes

Yes

Protein products

T-cell surface glycoprotein CD3 zeta chain

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Primary sclerosing cholangitis

Database cross reference

HGNC:1677
MIM:186780
Ensembl:ENSG00000198821
HPRD:01729
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

GO annotation

GO:0004888

transmembrane receptor activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0007166

cell surface receptor linked signaling pathway

GO:0016021

integral to membrane

GO:0016032

viral reproduction

GO:0031295

T cell costimulation

GO:0042101

T cell receptor complex

GO:0042105

alpha-beta T cell receptor complex

GO:0042802

identical protein binding

GO:0042803

protein homodimerization activity

GO:0044419

interspecies interaction between organisms

GO:0050690

regulation of defense response to virus by virus

GO:0050776

regulation of immune response

GO:0050852

T cell receptor signaling pathway