Gene basic information
| LiverAtlas Gene ID |
HuLG000652 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD4 |
|
Synonyms |
CD4mut |
|
Gene name |
CD4 molecule |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12pter-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA, FLJ79547, highly similar to T-cell surface glycoprotein CD4 cDNA FLJ50658, highly similar to T-cell surface glycoprotein CD4 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1678
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001816 |
cytokine production |
|
GO:0001948 |
glycoprotein binding |
|
GO:0004872 |
receptor activity |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005201 |
extracellular matrix structural constituent |
|
GO:0005515 |
protein binding |
|
GO:0005769 |
early endosome |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005886 |
plasma membrane |
|
GO:0006948 |
induction by virus of host cell-cell fusion |
|
GO:0006955 |
immune response |
|
GO:0007155 |
cell adhesion |
|
GO:0007165 |
signal transduction |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007167 |
enzyme linked receptor protein signaling pathway |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0008270 |
zinc ion binding |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0015026 |
coreceptor activity |
|
GO:0016021 |
integral to membrane |
|
GO:0016032 |
viral reproduction |
|
GO:0019059 |
initiation of viral infection |
|
GO:0019901 |
protein kinase binding |
|
GO:0030217 |
T cell differentiation |
|
GO:0030260 |
entry into host cell |
|
GO:0031295 |
T cell costimulation |
|
GO:0032507 |
maintenance of protein location in cell |
|
GO:0042101 |
T cell receptor complex |
|
GO:0042289 |
MHC class II protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045058 |
T cell selection |
|
GO:0045086 |
positive regulation of interleukin-2 biosynthetic process |
|
GO:0045121 |
membrane raft |
|
GO:0045234 |
protein palmitoleylation |
|
GO:0045860 |
positive regulation of protein kinase activity |
|
GO:0050690 |
regulation of defense response to virus by virus |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0050850 |
positive regulation of calcium-mediated signaling |
|
GO:0050852 |
T cell receptor signaling pathway |
|
GO:0050863 |
regulation of T cell activation |
|
GO:0051789 |
response to protein stimulus |
