Gene basic information
| LiverAtlas Gene ID |
HuLG000657 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD8A |
|
Synonyms |
CD8|Leu2|MAL|p32 |
|
Gene name |
CD8a molecule |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2p12 |
|
Known cancer genes |
Yes |
|
Protein products |
T-cell surface glycoprotein CD8 alpha chain cDNA FLJ42162 fis, clone THYMU2005303, highly similar to T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1706
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002456 |
T cell mediated immunity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006955 |
immune response |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0015026 |
coreceptor activity |
|
GO:0019882 |
antigen processing and presentation |
|
GO:0019901 |
protein kinase binding |
|
GO:0042101 |
T cell receptor complex |
|
GO:0042110 |
T cell activation |
|
GO:0042288 |
MHC class I protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0045065 |
cytotoxic T cell differentiation |
|
GO:0050776 |
regulation of immune response |
|
GO:0050850 |
positive regulation of calcium-mediated signaling |
