Gene basic information
| LiverAtlas Gene ID |
HuLG000667 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD80 |
|
Synonyms |
B7|BB1|CD28LG|CD28LG1|LAB7 |
|
Gene name |
CD80 molecule |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3q13.3-q21 |
|
Known cancer genes |
Yes |
|
Protein products |
CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), isoform CRA a |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1700
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005515 |
protein binding |
|
GO:0005886 |
plasma membrane |
|
GO:0007267 |
cell-cell signaling |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0009967 |
positive regulation of signal transduction |
|
GO:0015026 |
coreceptor activity |
|
GO:0016021 |
integral to membrane |
|
GO:0031295 |
T cell costimulation |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0042110 |
T cell activation |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045086 |
positive regulation of interleukin-2 biosynthetic process |
|
GO:0045425 |
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process |
|
GO:0045627 |
positive regulation of T-helper 1 cell differentiation |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0046641 |
positive regulation of alpha-beta T cell proliferation |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
