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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000668

Entrez Gene ID

942

Official Gene Symbol

CD86

Synonyms

B7N2|B70|CD28LG2|LAB72|MGC34413

Gene name

CD86 molecule

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q21

Known cancer genes

Yes

Protein products

T-lymphocyte activation antigen CD86

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Primary biliary cirrhosis

Hepatocellular carcinoma

Primary sclerosing cholangitis

Database cross reference

HGNC:1705
MIM:601020
Ensembl:ENSG00000114013
HPRD:03011
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001878

response to yeast

GO:0002224

toll-like receptor signaling pathway

GO:0004872

receptor activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0006955

immune response

GO:0007267

cell-cell signaling

GO:0007568

aging

GO:0008284

positive regulation of cell proliferation

GO:0009897

external side of plasma membrane

GO:0015026

coreceptor activity

GO:0016021

integral to membrane

GO:0031295

T cell costimulation

GO:0032496

response to lipopolysaccharide

GO:0034341

response to interferon-gamma

GO:0042098

T cell proliferation

GO:0042110

T cell activation

GO:0042113

B cell activation

GO:0043017

positive regulation of lymphotoxin A biosynthetic process

GO:0043231

intracellular membrane-bounded organelle

GO:0044419

interspecies interaction between organisms

GO:0045086

positive regulation of interleukin-2 biosynthetic process

GO:0045404

positive regulation of interleukin-4 biosynthetic process

GO:0045630

positive regulation of T-helper 2 cell differentiation

GO:0045893

positive regulation of transcription, DNA-dependent