HuLG000669

Entrez Gene ID

943

Official Gene Symbol

TNFRSF8

Synonyms

CD30|D1S166E|KiN1

Gene name

tumor necrosis factor receptor superfamily, member 8

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36

Known cancer genes

Yes

Protein products

TNFRSF8 protein

Tumor necrosis factor receptor superfamily member 8

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Primary biliary cirrhosis

Database cross reference

HGNC:11923
MIM:153243
Ensembl:ENSG00000120949
HPRD:01074
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

GO annotation

GO:0004888

transmembrane receptor activity

GO:0005031

tumor necrosis factor receptor activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0007165

signal transduction

GO:0008285

negative regulation of cell proliferation

GO:0016021

integral to membrane

GO:0033209

tumor necrosis factor-mediated signaling pathway

GO:0042535

positive regulation of tumor necrosis factor biosynthetic process

GO:0043065

positive regulation of apoptosis

GO:0045556

positive regulation of TRAIL biosynthetic process

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO:0071260

cellular response to mechanical stimulus