Gene basic information
| LiverAtlas Gene ID |
HuLG000674 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD36 |
|
Synonyms |
CHDS7|FAT|GP3B|GP4|GPIV|PASIV|SCARB3 |
|
Gene name |
CD36 molecule (thrombospondin receptor) |
|
Gene Type |
protein-coding |
|
Chromosome |
7 |
|
Genomics Location |
7q11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
CD36 antigen (Collagen type I receptor, thrombospondin receptor) Platelet glycoprotein IV variant Platelet glycoprotein IV variant |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis |
|
Database cross reference |
HGNC:1663
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001954 |
positive regulation of cell-matrix adhesion |
|
GO:0002576 |
platelet degranulation |
|
GO:0005041 |
low-density lipoprotein receptor activity |
|
GO:0005624 |
membrane fraction |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006810 |
transport |
|
GO:0006910 |
phagocytosis, recognition |
|
GO:0007155 |
cell adhesion |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007263 |
nitric oxide mediated signal transduction |
|
GO:0007596 |
blood coagulation |
|
GO:0008035 |
high-density lipoprotein particle binding |
|
GO:0008289 |
lipid binding |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0009986 |
cell surface |
|
GO:0010629 |
negative regulation of gene expression |
|
GO:0010744 |
positive regulation of macrophage derived foam cell differentiation |
|
GO:0010886 |
positive regulation of cholesterol storage |
|
GO:0015911 |
plasma membrane long-chain fatty acid transport |
|
GO:0019915 |
lipid storage |
|
GO:0019934 |
cGMP-mediated signaling |
|
GO:0030168 |
platelet activation |
|
GO:0030169 |
low-density lipoprotein particle binding |
|
GO:0030194 |
positive regulation of blood coagulation |
|
GO:0030301 |
cholesterol transport |
|
GO:0031092 |
platelet alpha granule membrane |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032760 |
positive regulation of tumor necrosis factor production |
|
GO:0034381 |
plasma lipoprotein particle clearance |
|
GO:0034383 |
low-density lipoprotein particle clearance |
|
GO:0035634 |
response to stilbenoid |
|
GO:0042953 |
lipoprotein transport |
|
GO:0042992 |
negative regulation of transcription factor import into nucleus |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043277 |
apoptotic cell clearance |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0044130 |
negative regulation of growth of symbiont in host |
|
GO:0045121 |
membrane raft |
|
GO:0050431 |
transforming growth factor beta binding |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0050830 |
defense response to Gram-positive bacterium |
|
GO:0051636 |
Gram-negative bacterial cell surface binding |
|
GO:0051637 |
Gram-positive bacterial cell surface binding |
|
GO:0060100 |
positive regulation of phagocytosis, engulfment |
|
GO:0060907 |
positive regulation of macrophage cytokine production |
|
GO:0070053 |
thrombospondin receptor activity |
|
GO:0070892 |
lipoteichoic acid receptor activity |
|
GO:0071221 |
cellular response to bacterial lipopeptide |
|
GO:0071222 |
cellular response to lipopolysaccharide |
|
GO:0071223 |
cellular response to lipoteichoic acid |
|
GO:0071447 |
cellular response to hydroperoxide |
|
GO:0071813 |
lipoprotein particle binding |
|
GO:2000121 |
regulation of removal of superoxide radicals |
