HuLG000675

Entrez Gene ID

949

Official Gene Symbol

SCARB1

Synonyms

CD36L1|CLAN1|CLA1|HDLQTL6|MGC138242|SRNBI|SRB1

Gene name

scavenger receptor class B, member 1

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.31

Known cancer genes

Yes

Protein products

Scavenger receptor class B member 1

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1664
MIM:601040
Ensembl:ENSG00000073060
HPRD:03024
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0000299

integral to membrane of membrane fraction

GO:0001530

lipopolysaccharide binding

GO:0001786

phosphatidylserine binding

GO:0001875

lipopolysaccharide receptor activity

GO:0001935

endothelial cell proliferation

GO:0004872

receptor activity

GO:0005215

transporter activity

GO:0005515

protein binding

GO:0005545

1-phosphatidylinositol binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0005901

caveola

GO:0006629

lipid metabolic process

GO:0006702

androgen biosynthetic process

GO:0006707

cholesterol catabolic process

GO:0006810

transport

GO:0006869

lipid transport

GO:0007155

cell adhesion

GO:0009986

cell surface

GO:0010595

positive regulation of endothelial cell migration

GO:0010886

positive regulation of cholesterol storage

GO:0015920

lipopolysaccharide transport

GO:0030169

low-density lipoprotein particle binding

GO:0031528

microvillus membrane

GO:0031663

lipopolysaccharide-mediated signaling pathway

GO:0032497

detection of lipopolysaccharide

GO:0033344

cholesterol efflux

GO:0034185

apolipoprotein binding

GO:0034186

apolipoprotein A-I binding

GO:0034375

high-density lipoprotein particle remodeling

GO:0034384

high-density lipoprotein particle clearance

GO:0042060

wound healing

GO:0042157

lipoprotein metabolic process

GO:0042632

cholesterol homeostasis

GO:0042803

protein homodimerization activity

GO:0043534

blood vessel endothelial cell migration

GO:0043654

recognition of apoptotic cell

GO:0043691

reverse cholesterol transport

GO:0044419

interspecies interaction between organisms

GO:0050764

regulation of phagocytosis

GO:0051000

positive regulation of nitric-oxide synthase activity

GO:0051856

adhesion to symbiont

GO:0070328

triglyceride homeostasis

GO:0070506

high-density lipoprotein particle receptor activity

GO:0070508

cholesterol import