Gene basic information
| LiverAtlas Gene ID |
HuLG000684 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD40 |
|
Synonyms |
Bp50|CDW40|MGC9013|TNFRSF5|p50 |
|
Gene name |
CD40 molecule, TNF receptor superfamily member 5 |
|
Gene Type |
protein-coding |
|
Chromosome |
20 |
|
Genomics Location |
20q12-q13.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11919
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002768 |
immune response-regulating cell surface receptor signaling pathway |
|
GO:0004871 |
signal transducer activity |
|
GO:0004872 |
receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006461 |
protein complex assembly |
|
GO:0006954 |
inflammatory response |
|
GO:0007165 |
signal transduction |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0009898 |
internal side of plasma membrane |
|
GO:0019899 |
enzyme binding |
|
GO:0030168 |
platelet activation |
|
GO:0030890 |
positive regulation of B cell proliferation |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0035631 |
CD40 receptor complex |
|
GO:0042100 |
B cell proliferation |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043231 |
intracellular membrane-bounded organelle |
|
GO:0048304 |
positive regulation of isotype switching to IgG isotypes |
|
GO:0050776 |
regulation of immune response |
|
GO:0051023 |
regulation of immunoglobulin secretion |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:2000353 |
positive regulation of endothelial cell apoptosis |
