Gene basic information
| LiverAtlas Gene ID |
HuLG000685 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD40LG |
|
Synonyms |
CD154|CD40L|HIGM1|IGM|IMD3|TNBAM|TNFSF5|TRAP|gp39|hCD40L |
|
Gene name |
CD40 ligand |
|
Gene Type |
protein-coding |
|
Chromosome |
0 |
|
Genomics Location |
Xq26 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11935
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002839 |
positive regulation of immune response to tumor cell |
|
GO:0005125 |
cytokine activity |
|
GO:0005164 |
tumor necrosis factor receptor binding |
|
GO:0005174 |
CD40 receptor binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005625 |
soluble fraction |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006954 |
inflammatory response |
|
GO:0007159 |
leukocyte cell-cell adhesion |
|
GO:0016021 |
integral to membrane |
|
GO:0030168 |
platelet activation |
|
GO:0030183 |
B cell differentiation |
|
GO:0030890 |
positive regulation of B cell proliferation |
|
GO:0032729 |
positive regulation of interferon-gamma production |
|
GO:0032733 |
positive regulation of interleukin-10 production |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0042100 |
B cell proliferation |
|
GO:0045190 |
isotype switching |
|
GO:0045348 |
positive regulation of MHC class II biosynthetic process |
|
GO:0050776 |
regulation of immune response |
|
GO:0051023 |
regulation of immunoglobulin secretion |
|
GO:2000353 |
positive regulation of endothelial cell apoptosis |
