Gene basic information
| LiverAtlas Gene ID |
HuLG000686 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CD44 |
|
Synonyms |
CDW44|CSPG8|ECMRNIII|HCELL|HUTCHNI|IN|LHR|MC56|MDU2|MDU3|MGC10468|MIC4|Pgp1 |
|
Gene name |
CD44 molecule (Indian blood group) |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11p13 |
|
Known cancer genes |
Yes |
|
Protein products |
CD44 antigen (Indian blood group), isoform CRA g CD44 molecule (Indian blood group) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1681
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005518 |
collagen binding |
|
GO:0005540 |
hyaluronic acid binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0007160 |
cell-matrix adhesion |
|
GO:0009986 |
cell surface |
|
GO:0016337 |
cell-cell adhesion |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043518 |
negative regulation of DNA damage response, signal transduction by p53 class mediator |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0060333 |
interferon-gamma-mediated signaling pathway |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
