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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000709

Entrez Gene ID

990

Official Gene Symbol

CDC6

Synonyms

CDC18L|HsCDC18|HsCDC6

Gene name

cell division cycle 6 homolog (S. cerevisiae)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q21.3

Known cancer genes

Yes

Protein products

Cell division control protein 6 homolog

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1744
MIM:602627
Ensembl:ENSG00000094804
HPRD:04022
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000076

DNA replication checkpoint

GO:0000079

regulation of cyclin-dependent protein kinase activity

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000083

regulation of transcription involved in G1/S phase of mitotic cell cycle

GO:0000084

S phase of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000216

M/G1 transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0000922

spindle pole

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006260

DNA replication

GO:0007067

mitosis

GO:0007089

traversing start control point of mitotic cell cycle

GO:0008156

negative regulation of DNA replication

GO:0008285

negative regulation of cell proliferation

GO:0017111

nucleoside-triphosphatase activity

GO:0019900

kinase binding

GO:0051233

spindle midzone

GO:0051301

cell division

GO:0051984

positive regulation of chromosome segregation

GO:0071777

positive regulation of cell cycle cytokinesis

GO:0090007

regulation of mitotic anaphase