Gene basic information
LiverAtlas Gene ID |
HuLG000709 |
Entrez Gene ID |
|
Official Gene Symbol |
CDC6 |
Synonyms |
CDC18L|HsCDC18|HsCDC6 |
Gene name |
cell division cycle 6 homolog (S. cerevisiae) |
Gene Type |
protein-coding |
Chromosome |
17 |
Genomics Location |
17q21.3 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:1744
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000075 |
cell cycle checkpoint |
GO:0000076 |
DNA replication checkpoint |
GO:0000079 |
regulation of cyclin-dependent protein kinase activity |
GO:0000082 |
G1/S transition of mitotic cell cycle |
GO:0000083 |
regulation of transcription involved in G1/S phase of mitotic cell cycle |
GO:0000084 |
S phase of mitotic cell cycle |
GO:0000166 |
nucleotide binding |
GO:0000216 |
M/G1 transition of mitotic cell cycle |
GO:0000278 |
mitotic cell cycle |
GO:0000922 |
spindle pole |
GO:0003682 |
chromatin binding |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005634 |
nucleus |
GO:0005654 |
nucleoplasm |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0006260 |
DNA replication |
GO:0007067 |
mitosis |
GO:0007089 |
traversing start control point of mitotic cell cycle |
GO:0008156 |
negative regulation of DNA replication |
GO:0008285 |
negative regulation of cell proliferation |
GO:0017111 |
nucleoside-triphosphatase activity |
GO:0019900 |
kinase binding |
GO:0051233 |
spindle midzone |
GO:0051301 |
cell division |
GO:0051984 |
positive regulation of chromosome segregation |
GO:0071777 |
positive regulation of cell cycle cytokinesis |
GO:0090007 |
regulation of mitotic anaphase |