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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000711

Entrez Gene ID

993

Official Gene Symbol

CDC25A

Synonyms

CDC25A2

Gene name

cell division cycle 25 homolog A (S. pombe)

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p21

Known cancer genes

Yes

Protein products

CDC25A2-CAG isoform

M-phase inducer phosphatase 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1725
MIM:116947
Ensembl:ENSG00000164045
HPRD:00305
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000079

regulation of cyclin-dependent protein kinase activity

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000084

S phase of mitotic cell cycle

GO:0000086

G2/M transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0004721

phosphoprotein phosphatase activity

GO:0004725

protein tyrosine phosphatase activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006260

DNA replication

GO:0007067

mitosis

GO:0008283

cell proliferation

GO:0016787

hydrolase activity

GO:0034644

cellular response to UV

GO:0051301

cell division