Gene basic information
LiverAtlas Gene ID |
HuLG000716 |
Entrez Gene ID |
|
Official Gene Symbol |
CDC42 |
Synonyms |
CDC42Hs|G25K |
Gene name |
cell division cycle 42 (GTP binding protein, 25kDa) |
Gene Type |
protein-coding |
Chromosome |
1 |
Genomics Location |
1p36.1 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:1736
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0003924 |
GTPase activity |
GO:0005515 |
protein binding |
GO:0005525 |
GTP binding |
GO:0005622 |
intracellular |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0005886 |
plasma membrane |
GO:0006184 |
GTP catabolic process |
GO:0007163 |
establishment or maintenance of cell polarity |
GO:0007173 |
epidermal growth factor receptor signaling pathway |
GO:0007264 |
small GTPase mediated signal transduction |
GO:0007411 |
axon guidance |
GO:0007596 |
blood coagulation |
GO:0030036 |
actin cytoskeleton organization |
GO:0030175 |
filopodium |
GO:0030225 |
macrophage differentiation |
GO:0031274 |
positive regulation of pseudopodium assembly |
GO:0031295 |
T cell costimulation |
GO:0031333 |
negative regulation of protein complex assembly |
GO:0031996 |
thioesterase binding |
GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
GO:0042692 |
muscle cell differentiation |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
GO:0051149 |
positive regulation of muscle cell differentiation |