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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000716

Entrez Gene ID

998

Official Gene Symbol

CDC42

Synonyms

CDC42Hs|G25K

Gene name

cell division cycle 42 (GTP binding protein, 25kDa)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.1

Known cancer genes

Yes

Protein products

Cell division control protein 42 homolog

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1736
MIM:116952
Ensembl:ENSG00000070831
HPRD:00309
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003924

GTPase activity

GO:0005515

protein binding

GO:0005525

GTP binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006184

GTP catabolic process

GO:0007163

establishment or maintenance of cell polarity

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0007264

small GTPase mediated signal transduction

GO:0007411

axon guidance

GO:0007596

blood coagulation

GO:0030036

actin cytoskeleton organization

GO:0030175

filopodium

GO:0030225

macrophage differentiation

GO:0031274

positive regulation of pseudopodium assembly

GO:0031295

T cell costimulation

GO:0031333

negative regulation of protein complex assembly

GO:0031996

thioesterase binding

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

GO:0042692

muscle cell differentiation

GO:0051056

regulation of small GTPase mediated signal transduction

GO:0051149

positive regulation of muscle cell differentiation