Gene basic information
LiverAtlas Gene ID |
HuLG000717 |
Entrez Gene ID |
|
Official Gene Symbol |
CDH1 |
Synonyms |
ArcN1|CD324|CDHE|ECAD|LCAM|UVO |
Gene name |
cadherin 1, type 1, E-cadherin (epithelial) |
Gene Type |
protein-coding |
Chromosome |
16 |
Genomics Location |
16q22.1 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:1748
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001701 |
in utero embryonic development |
GO:0001829 |
trophectodermal cell differentiation |
GO:0005509 |
calcium ion binding |
GO:0005515 |
protein binding |
GO:0005737 |
cytoplasm |
GO:0005886 |
plasma membrane |
GO:0005913 |
cell-cell adherens junction |
GO:0005925 |
focal adhesion |
GO:0006915 |
apoptosis |
GO:0006921 |
cellular component disassembly involved in apoptosis |
GO:0007156 |
homophilic cell adhesion |
GO:0007416 |
synapse assembly |
GO:0008013 |
beta-catenin binding |
GO:0009636 |
response to toxin |
GO:0009898 |
internal side of plasma membrane |
GO:0009986 |
cell surface |
GO:0010033 |
response to organic substance |
GO:0015629 |
actin cytoskeleton |
GO:0016021 |
integral to membrane |
GO:0016235 |
aggresome |
GO:0016323 |
basolateral plasma membrane |
GO:0016328 |
lateral plasma membrane |
GO:0016337 |
cell-cell adhesion |
GO:0016342 |
catenin complex |
GO:0019538 |
protein metabolic process |
GO:0019903 |
protein phosphatase binding |
GO:0019904 |
protein domain specific binding |
GO:0021983 |
pituitary gland development |
GO:0022408 |
negative regulation of cell-cell adhesion |
GO:0030054 |
cell junction |
GO:0031175 |
neuron projection development |
GO:0033561 |
regulation of water loss via skin |
GO:0034329 |
cell junction assembly |
GO:0034332 |
adherens junction organization |
GO:0042153 |
RPTP-like protein binding |
GO:0042493 |
response to drug |
GO:0042993 |
positive regulation of transcription factor import into nucleus |
GO:0043281 |
regulation of caspase activity |
GO:0043296 |
apical junction complex |
GO:0045177 |
apical part of cell |
GO:0045216 |
cell-cell junction organization |
GO:0045295 |
gamma-catenin binding |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0050776 |
regulation of immune response |
GO:0050839 |
cell adhesion molecule binding |
GO:0051260 |
protein homooligomerization |
GO:0060662 |
salivary gland cavitation |
GO:0060693 |
regulation of branching involved in salivary gland morphogenesis |
GO:0070830 |
tight junction assembly |
GO:0071285 |
cellular response to lithium ion |
GO:0071681 |
cellular response to indole-3-methanol |
GO:2000008 |
regulation of protein localization at cell surface |