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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000717

Entrez Gene ID

999

Official Gene Symbol

CDH1

Synonyms

ArcN1|CD324|CDHE|ECAD|LCAM|UVO

Gene name

cadherin 1, type 1, E-cadherin (epithelial)

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q22.1

Known cancer genes

Yes

Protein products

Cadherin 1, type 1, E-cadherin (Epithelial), isoform CRA b

Truncated E-cadherin

Cadherin-1

E-cadherin 1

Cadherin 1, type 1, E-cadherin (Epithelial), isoform CRA c

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1748
MIM:192090
Ensembl:ENSG00000039068
HPRD:01885
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001701

in utero embryonic development

GO:0001829

trophectodermal cell differentiation

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005913

cell-cell adherens junction

GO:0005925

focal adhesion

GO:0006915

apoptosis

GO:0006921

cellular component disassembly involved in apoptosis

GO:0007156

homophilic cell adhesion

GO:0007416

synapse assembly

GO:0008013

beta-catenin binding

GO:0009636

response to toxin

GO:0009898

internal side of plasma membrane

GO:0009986

cell surface

GO:0010033

response to organic substance

GO:0015629

actin cytoskeleton

GO:0016021

integral to membrane

GO:0016235

aggresome

GO:0016323

basolateral plasma membrane

GO:0016328

lateral plasma membrane

GO:0016337

cell-cell adhesion

GO:0016342

catenin complex

GO:0019538

protein metabolic process

GO:0019903

protein phosphatase binding

GO:0019904

protein domain specific binding

GO:0021983

pituitary gland development

GO:0022408

negative regulation of cell-cell adhesion

GO:0030054

cell junction

GO:0031175

neuron projection development

GO:0033561

regulation of water loss via skin

GO:0034329

cell junction assembly

GO:0034332

adherens junction organization

GO:0042153

RPTP-like protein binding

GO:0042493

response to drug

GO:0042993

positive regulation of transcription factor import into nucleus

GO:0043281

regulation of caspase activity

GO:0043296

apical junction complex

GO:0045177

apical part of cell

GO:0045216

cell-cell junction organization

GO:0045295

gamma-catenin binding

GO:0048471

perinuclear region of cytoplasm

GO:0050776

regulation of immune response

GO:0050839

cell adhesion molecule binding

GO:0051260

protein homooligomerization

GO:0060662

salivary gland cavitation

GO:0060693

regulation of branching involved in salivary gland morphogenesis

GO:0070830

tight junction assembly

GO:0071285

cellular response to lithium ion

GO:0071681

cellular response to indole-3-methanol

GO:2000008

regulation of protein localization at cell surface