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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000760

Entrez Gene ID

1050

Official Gene Symbol

CEBPA

Synonyms

C/EBPNalpha|CEBP

Gene name

CCAAT/enhancer binding protein (C/EBP), alpha

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.1

Known cancer genes

Yes

Protein products

CCAAT/enhancer-binding protein alpha

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:1833
MIM:116897
Ensembl:ENSG00000245848
HPRD:00296
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000050

urea cycle

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0001889

liver development

GO:0001892

embryonic placenta development

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0006091

generation of precursor metabolites and energy

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0006366

transcription from RNA polymerase II promoter

GO:0006953

acute-phase response

GO:0007005

mitochondrion organization

GO:0007584

response to nutrient

GO:0008134

transcription factor binding

GO:0008203

cholesterol metabolic process

GO:0008285

negative regulation of cell proliferation

GO:0016363

nuclear matrix

GO:0019221

cytokine-mediated signaling pathway

GO:0019904

protein domain specific binding

GO:0030099

myeloid cell differentiation

GO:0030225

macrophage differentiation

GO:0030324

lung development

GO:0031100

organ regeneration

GO:0032403

protein complex binding

GO:0033274

response to vitamin B2

GO:0035189

Rb-E2F complex

GO:0042803

protein homodimerization activity

GO:0043565

sequence-specific DNA binding

GO:0044419

interspecies interaction between organisms

GO:0045600

positive regulation of fat cell differentiation

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0045945

positive regulation of transcription from RNA polymerase III promoter

GO:0046982

protein heterodimerization activity

GO:0048469

cell maturation

GO:0050872

white fat cell differentiation

GO:0050873

brown fat cell differentiation

GO:0051384

response to glucocorticoid stimulus

GO:0071285

cellular response to lithium ion

GO:0071407

cellular response to organic cyclic compound