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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000765

Entrez Gene ID

1056

Official Gene Symbol

CEL

Synonyms

BAL|BSDL|BSSL|CELL|CEase|FAP|FAPP|LIPA|MODY8

Gene name

carboxyl ester lipase (bile salt-stimulated lipase)

Gene Type

protein-coding

Chromosome

9

Genomics Location

9q34.3

Known cancer genes

Yes

Protein products

Bile salt-activated lipase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1848
MIM:114840
Ensembl:ENSG00000170835
HPRD:07509
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003824

catalytic activity

GO:0004091

carboxylesterase activity

GO:0004622

lysophospholipase activity

GO:0004771

sterol esterase activity

GO:0004806

triglyceride lipase activity

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005791

rough endoplasmic reticulum

GO:0005792

microsome

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0006629

lipid metabolic process

GO:0006641

triglyceride metabolic process

GO:0006707

cholesterol catabolic process

GO:0008201

heparin binding

GO:0009062

fatty acid catabolic process

GO:0016042

lipid catabolic process

GO:0016787

hydrolase activity

GO:0018350

protein esterification

GO:0030157

pancreatic juice secretion

GO:0030299

intestinal cholesterol absorption

GO:0032403

protein complex binding

GO:0042588

zymogen granule

GO:0043208

glycosphingolipid binding

GO:0043234

protein complex

GO:0044241

lipid digestion

GO:0044258

intestinal lipid catabolic process

GO:0045121

membrane raft

GO:0046514

ceramide catabolic process

GO:0047372

acylglycerol lipase activity

GO:0050253

retinyl-palmitate esterase activity

GO:0050804

regulation of synaptic transmission