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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000771

Entrez Gene ID

1063

Official Gene Symbol

CENPF

Synonyms

CENF|PRO1779|hcpN1

Gene name

centromere protein F, 350/400kDa (mitosin)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q32-q41

Known cancer genes

Yes

Protein products

Centromere protein F

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1857
MIM:600236
Ensembl:ENSG00000117724
HPRD:02582
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000085

G2 phase of mitotic cell cycle

GO:0000087

M phase of mitotic cell cycle

GO:0000236

mitotic prometaphase

GO:0000278

mitotic cell cycle

GO:0000775

chromosome, centromeric region

GO:0000776

kinetochore

GO:0000785

chromatin

GO:0000922

spindle pole

GO:0000940

condensed chromosome outer kinetochore

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005635

nuclear envelope

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0005819

spindle

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0006260

DNA replication

GO:0007059

chromosome segregation

GO:0007094

mitotic cell cycle spindle assembly checkpoint

GO:0007275

multicellular organismal development

GO:0007517

muscle organ development

GO:0008022

protein C-terminus binding

GO:0008134

transcription factor binding

GO:0008283

cell proliferation

GO:0010389

regulation of G2/M transition of mitotic cell cycle

GO:0015031

protein transport

GO:0016202

regulation of striated muscle tissue development

GO:0016363

nuclear matrix

GO:0030154

cell differentiation

GO:0030496

midbody

GO:0042493

response to drug

GO:0042803

protein homodimerization activity

GO:0045502

dynein binding

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0048471

perinuclear region of cytoplasm

GO:0051301

cell division

GO:0051310

metaphase plate congression

GO:0051382

kinetochore assembly