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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000794

Entrez Gene ID

1108

Official Gene Symbol

CHD4

Synonyms

DKFZp686E06161|MiN2b|Mi2NBETA

Gene name

chromodomain helicase DNA binding protein 4

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13

Known cancer genes

Yes

Protein products

cDNA FLJ16830 fis, clone UTERU3022536, highly similar to Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-)

Chromodomain-helicase-DNA-binding protein 4

CHD4 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1919
MIM:603277
Ensembl:ENSG00000111642
HPRD:04472
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003677

DNA binding

GO:0004003

ATP-dependent DNA helicase activity

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005815

microtubule organizing center

GO:0005856

cytoskeleton

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0008134

transcription factor binding

GO:0008270

zinc ion binding

GO:0016568

chromatin modification

GO:0016581

NuRD complex

GO:0016787

hydrolase activity

GO:0016818

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO:0046872

metal ion binding