Gene basic information
| LiverAtlas Gene ID |
HuLG000795 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AKR1C4 |
|
Synonyms |
3NalphaNHSD|C11|CDR|CHDR|DDN4|DD4|HAKRA|MGC22581 |
|
Gene name |
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydr |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10p15.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:387
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004033 |
aldo-keto reductase (NADP) activity |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006699 |
bile acid biosynthetic process |
|
GO:0008202 |
steroid metabolic process |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0008209 |
androgen metabolic process |
|
GO:0009055 |
electron carrier activity |
|
GO:0015125 |
bile acid transmembrane transporter activity |
|
GO:0015721 |
bile acid and bile salt transport |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0047042 |
androsterone dehydrogenase (B-specific) activity |
|
GO:0047743 |
chlordecone reductase activity |
