Gene basic information
| LiverAtlas Gene ID |
HuLG000796 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CHEK1 |
|
Synonyms |
CHK1 |
|
Gene name |
CHK1 checkpoint homolog (S. pombe) |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q24.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1925
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000077 |
DNA damage checkpoint |
|
GO:0000079 |
regulation of cyclin-dependent protein kinase activity |
|
GO:0000086 |
G2/M transition of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0000781 |
chromosome, telomeric region |
|
GO:0000794 |
condensed nuclear chromosome |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005657 |
replication fork |
|
GO:0005737 |
cytoplasm |
|
GO:0005815 |
microtubule organizing center |
|
GO:0005856 |
cytoskeleton |
|
GO:0006260 |
DNA replication |
|
GO:0006281 |
DNA repair |
|
GO:0006975 |
DNA damage induced protein phosphorylation |
|
GO:0007049 |
cell cycle |
|
GO:0007131 |
reciprocal meiotic recombination |
|
GO:0007276 |
gamete generation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0016301 |
kinase activity |
|
GO:0016310 |
phosphorylation |
|
GO:0031572 |
G2/M transition DNA damage checkpoint |
|
GO:0033261 |
regulation of S phase |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:0071310 |
cellular response to organic substance |
|
GO:0071313 |
cellular response to caffeine |
|
GO:0090399 |
replicative senescence |
