HuLG000815

Entrez Gene ID

1134

Official Gene Symbol

CHRNA1

Synonyms

ACHRA|ACHRD|CHRNA|CMS2A|FCCMS|SCCMS

Gene name

cholinergic receptor, nicotinic, alpha 1 (muscle)

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q24-q32

Known cancer genes

Yes

Protein products

Acetylcholine receptor subunit alpha

Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA a

Database cross reference

HGNC:1955
MIM:100690
Ensembl:ENSG00000138435
HPRD:00007
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

GO annotation

GO:0003009

skeletal muscle contraction

GO:0004872

receptor activity

GO:0004889

nicotinic acetylcholine-activated cation-selective channel activity

GO:0005216

ion channel activity

GO:0005230

extracellular ligand-gated ion channel activity

GO:0005886

plasma membrane

GO:0005892

nicotinic acetylcholine-gated receptor-channel complex

GO:0006810

transport

GO:0006811

ion transport

GO:0007165

signal transduction

GO:0007268

synaptic transmission

GO:0007274

neuromuscular synaptic transmission

GO:0007528

neuromuscular junction development

GO:0009986

cell surface

GO:0015464

acetylcholine receptor activity

GO:0016021

integral to membrane

GO:0019228

regulation of action potential in neuron

GO:0030054

cell junction

GO:0031594

neuromuscular junction

GO:0042166

acetylcholine binding

GO:0042391

regulation of membrane potential

GO:0045211

postsynaptic membrane

GO:0046716

muscle cell homeostasis

GO:0048630

skeletal muscle tissue growth

GO:0050881

musculoskeletal movement

GO:0050905

neuromuscular process

GO:0070050

neuron homeostasis