Gene basic information
LiverAtlas Gene ID |
HuLG000828 |
Entrez Gene ID |
|
Official Gene Symbol |
CHUK |
Synonyms |
IKBKA|IKKNalpha|IKK1|IKKA|NFKBIKA|TCF16 |
Gene name |
conserved helix-loop-helix ubiquitous kinase |
Gene Type |
protein-coding |
Chromosome |
10 |
Genomics Location |
10q24-q25 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:1974
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0002011 |
morphogenesis of an epithelial sheet |
GO:0002224 |
toll-like receptor signaling pathway |
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
GO:0004672 |
protein kinase activity |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005634 |
nucleus |
GO:0005730 |
nucleolus |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0006468 |
protein phosphorylation |
GO:0006955 |
immune response |
GO:0007252 |
I-kappaB phosphorylation |
GO:0007595 |
lactation |
GO:0008063 |
Toll signaling pathway |
GO:0008384 |
IkappaB kinase activity |
GO:0009653 |
anatomical structure morphogenesis |
GO:0009898 |
internal side of plasma membrane |
GO:0030316 |
osteoclast differentiation |
GO:0033598 |
mammary gland epithelial cell proliferation |
GO:0034130 |
toll-like receptor 1 signaling pathway |
GO:0034134 |
toll-like receptor 2 signaling pathway |
GO:0034138 |
toll-like receptor 3 signaling pathway |
GO:0034142 |
toll-like receptor 4 signaling pathway |
GO:0035631 |
CD40 receptor complex |
GO:0042475 |
odontogenesis of dentine-containing tooth |
GO:0042802 |
identical protein binding |
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
GO:0043231 |
intracellular membrane-bounded organelle |
GO:0045087 |
innate immune response |
GO:0048011 |
nerve growth factor receptor signaling pathway |
GO:0048015 |
phosphatidylinositol-mediated signaling |
GO:0050852 |
T cell receptor signaling pathway |
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
GO:0060749 |
mammary gland alveolus development |