Gene basic information
| LiverAtlas Gene ID |
HuLG000854 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CLU |
|
Synonyms |
APOJ|CLI|KUB1|MGC24903|SGPN2|SGP2|SPN40|TRPMN2|TRPM2 |
|
Gene name |
clusterin |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8p21-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2095
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001836 |
release of cytochrome c from mitochondria |
|
GO:0002576 |
platelet degranulation |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005739 |
mitochondrion |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006956 |
complement activation |
|
GO:0006958 |
complement activation, classical pathway |
|
GO:0007596 |
blood coagulation |
|
GO:0008219 |
cell death |
|
GO:0009615 |
response to virus |
|
GO:0016887 |
ATPase activity |
|
GO:0030168 |
platelet activation |
|
GO:0031012 |
extracellular matrix |
|
GO:0031093 |
platelet alpha granule lumen |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0032463 |
negative regulation of protein homooligomerization |
|
GO:0034366 |
spherical high-density lipoprotein particle |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043691 |
reverse cholesterol transport |
|
GO:0045087 |
innate immune response |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0050821 |
protein stabilization |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051787 |
misfolded protein binding |
|
GO:0051788 |
response to misfolded protein |
|
GO:0061077 |
chaperone-mediated protein folding |
|
GO:2000060 |
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
