HuLG000869

Entrez Gene ID

1213

Official Gene Symbol

CLTC

Synonyms

CHC|CHC17|CLHN17|CLTCL2|Hc|KIAA0034

Gene name

clathrin, heavy chain (Hc)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q11-qter

Known cancer genes

Yes

Protein products

Clathrin heavy chain 1

CLTC protein

Database cross reference

HGNC:2092
MIM:118955
Ensembl:ENSG00000141367
HPRD:00350
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

GO annotation

GO:0005198

structural molecule activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005819

spindle

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006886

intracellular protein transport

GO:0006892

post-Golgi vesicle-mediated transport

GO:0006898

receptor-mediated endocytosis

GO:0007067

mitosis

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0007411

axon guidance

GO:0016044

cellular membrane organization

GO:0016192

vesicle-mediated transport

GO:0030118

clathrin coat

GO:0030130

clathrin coat of trans-Golgi network vesicle

GO:0030132

clathrin coat of coated pit

GO:0030136

clathrin-coated vesicle

GO:0030659

cytoplasmic vesicle membrane

GO:0031410

cytoplasmic vesicle

GO:0031623

receptor internalization

GO:0033572

transferrin transport

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

GO:0042470

melanosome

GO:0048011

nerve growth factor receptor signaling pathway