Gene basic information
LiverAtlas Gene ID |
HuLG000874 |
Entrez Gene ID |
|
Official Gene Symbol |
CCR5 |
Synonyms |
CCNCKRN5|CCCKR5|CD195|CKRN5|CKR5|CMKBR5|FLJ78003|IDDM22 |
Gene name |
chemokine (C-C motif) receptor 5 |
Gene Type |
protein-coding |
Chromosome |
3 |
Genomics Location |
3p21.31 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
Database cross reference |
HGNC:1606
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0002407 |
dendritic cell chemotaxis |
GO:0003779 |
actin binding |
GO:0004435 |
phosphatidylinositol phospholipase C activity |
GO:0004930 |
G-protein coupled receptor activity |
GO:0004950 |
chemokine receptor activity |
GO:0005515 |
protein binding |
GO:0005737 |
cytoplasm |
GO:0005768 |
endosome |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0006935 |
chemotaxis |
GO:0006954 |
inflammatory response |
GO:0006955 |
immune response |
GO:0006968 |
cellular defense response |
GO:0007166 |
cell surface receptor linked signaling pathway |
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
GO:0007204 |
elevation of cytosolic calcium ion concentration |
GO:0007267 |
cell-cell signaling |
GO:0009897 |
external side of plasma membrane |
GO:0009986 |
cell surface |
GO:0015026 |
coreceptor activity |
GO:0016032 |
viral reproduction |
GO:0016493 |
C-C chemokine receptor activity |
GO:0019059 |
initiation of viral infection |
GO:0030260 |
entry into host cell |
GO:0044419 |
interspecies interaction between organisms |