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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000874

Entrez Gene ID

1234

Official Gene Symbol

CCR5

Synonyms

CCNCKRN5|CCCKR5|CD195|CKRN5|CKR5|CMKBR5|FLJ78003|IDDM22

Gene name

chemokine (C-C motif) receptor 5

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p21.31

Known cancer genes

Yes

Protein products

C-C chemokine receptor type 5

C-C chemokine receptor type 5

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic liver cirrhosis

Biliary cirrhosis

Hepatocellular carcinoma

Liver fibrosis and liver cirrhosis caused by hepatitis B infection

Cross infection of hepatitis virus and HIV

Hepatocellular carcinoma

Database cross reference

HGNC:1606
MIM:601373
Ensembl:ENSG00000160791
HPRD:03223
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002407

dendritic cell chemotaxis

GO:0003779

actin binding

GO:0004435

phosphatidylinositol phospholipase C activity

GO:0004930

G-protein coupled receptor activity

GO:0004950

chemokine receptor activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005768

endosome

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006935

chemotaxis

GO:0006954

inflammatory response

GO:0006955

immune response

GO:0006968

cellular defense response

GO:0007166

cell surface receptor linked signaling pathway

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007204

elevation of cytosolic calcium ion concentration

GO:0007267

cell-cell signaling

GO:0009897

external side of plasma membrane

GO:0009986

cell surface

GO:0015026

coreceptor activity

GO:0016032

viral reproduction

GO:0016493

C-C chemokine receptor activity

GO:0019059

initiation of viral infection

GO:0030260

entry into host cell

GO:0044419

interspecies interaction between organisms