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Gene basic information

LiverAtlas Gene ID

HuLG000876

Entrez Gene ID

1236

Official Gene Symbol

CCR7

Synonyms

BLR2|CD197|CDw197|CMKBR7|EBI1

Gene name

chemokine (C-C motif) receptor 7

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q12-q21.2

Known cancer genes

Yes

Protein products

Chemokine (C-C motif) receptor 7

C-C chemokine receptor type 7

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Primary sclerosing cholangitis

Database cross reference

HGNC:1608
MIM:600242
Ensembl:ENSG00000126353
HPRD:02588
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

 

Ontology annotation

GO ID

GO annotation

GO:0001768

establishment of T cell polarity

GO:0001771

immunological synapse formation

GO:0001954

positive regulation of cell-matrix adhesion

GO:0002407

dendritic cell chemotaxis

GO:0002408

myeloid dendritic cell chemotaxis

GO:0002606

positive regulation of dendritic cell antigen processing and presentation

GO:0002885

positive regulation of hypersensitivity

GO:0002922

positive regulation of humoral immune response

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0005622

intracellular

GO:0005886

plasma membrane

GO:0006935

chemotaxis

GO:0006954

inflammatory response

GO:0006955

immune response

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007204

elevation of cytosolic calcium ion concentration

GO:0009897

external side of plasma membrane

GO:0010560

positive regulation of glycoprotein biosynthetic process

GO:0016021

integral to membrane

GO:0016493

C-C chemokine receptor activity

GO:0030838

positive regulation of actin filament polymerization

GO:0031274

positive regulation of pseudopodium assembly

GO:0031295

T cell costimulation

GO:0031529

ruffle organization

GO:0032649

regulation of interferon-gamma production

GO:0032735

positive regulation of interleukin-12 production

GO:0032862

activation of Rho GTPase activity

GO:0034695

response to prostaglandin E stimulus

GO:0035757

chemokine (C-C motif) ligand 19 binding

GO:0035758

chemokine (C-C motif) ligand 21 binding

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043552

positive regulation of phosphatidylinositol 3-kinase activity

GO:0045785

positive regulation of cell adhesion

GO:0045860

positive regulation of protein kinase activity

GO:0046330

positive regulation of JNK cascade

GO:0048469

cell maturation

GO:0050706

regulation of interleukin-1 beta secretion

GO:0051209

release of sequestered calcium ion into cytosol

GO:0051491

positive regulation of filopodium assembly

GO:0051897

positive regulation of protein kinase B signaling cascade

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO:0071731

response to nitric oxide

GO:0072610

interleukin-12 secretion

GO:0090023

positive regulation of neutrophil chemotaxis

GO:0097022

lymphocyte migration into lymph node

GO:2000107

negative regulation of leukocyte apoptosis

GO:2000147

positive regulation of cell motility