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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000881

Entrez Gene ID

1244

Official Gene Symbol

ABCC2

Synonyms

ABC30|CMOAT|DJS|KIAA1010|MRP2|cMRP

Gene name

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24

Known cancer genes

Yes

Protein products

Canalicular multispecific organic anion transporter 1

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Canalicular multispecific organic anion transporter

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Drug-induced hepatitis

Biliary cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Intrahepatic cholestasis

Hepatocellular carcinoma

Primary sclerosing cholangitis

Database cross reference

HGNC:53
MIM:601107
Ensembl:ENSG00000023839
HPRD:03065
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0005215

transporter activity

GO:0005524

ATP binding

GO:0005624

membrane fraction

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0008514

organic anion transmembrane transporter activity

GO:0015711

organic anion transport

GO:0016020

membrane

GO:0016324

apical plasma membrane

GO:0016887

ATPase activity

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO:0046581

intercellular canaliculus

GO:0055085

transmembrane transport