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Gene basic information

LiverAtlas Gene ID

HuLG000892

Entrez Gene ID

1268

Official Gene Symbol

CNR1

Synonyms

CANN6|CBNR|CB1|CB1A|CB1K5|CB1R|CNR

Gene name

cannabinoid receptor 1 (brain)

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q14-q15

Known cancer genes

Yes

Protein products

Cannabinoid receptor 1

Cannabinoid receptor 1

Related liver disease name

Liver fibrosis and liver cirrhosis

Biliary cirrhosis

Nonalcoholic steatohepatitis

Database cross reference

HGNC:2159
MIM:114610
Ensembl:ENSG00000118432
HPRD:00259
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

 

Ontology annotation

GO ID

GO annotation

GO:0002866

positive regulation of acute inflammatory response to antigenic stimulus

GO:0004872

receptor activity

GO:0004949

cannabinoid receptor activity

GO:0005515

protein binding

GO:0005792

microsome

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006950

response to stress

GO:0007187

G-protein signaling, coupled to cyclic nucleotide second messenger

GO:0007188

G-protein signaling, coupled to cAMP nucleotide second messenger

GO:0007283

spermatogenesis

GO:0007568

aging

GO:0007584

response to nutrient

GO:0007610

behavior

GO:0007613

memory

GO:0008144

drug binding

GO:0010976

positive regulation of neuron projection development

GO:0019216

regulation of lipid metabolic process

GO:0019233

sensory perception of pain

GO:0031622

positive regulation of fever generation

GO:0031999

negative regulation of fatty acid beta-oxidation

GO:0032228

regulation of synaptic transmission, GABAergic

GO:0032496

response to lipopolysaccharide

GO:0033004

negative regulation of mast cell activation

GO:0033602

negative regulation of dopamine secretion

GO:0035094

response to nicotine

GO:0042220

response to cocaine

GO:0043065

positive regulation of apoptosis

GO:0043271

negative regulation of ion transport

GO:0043278

response to morphine

GO:0045471

response to ethanol

GO:0045759

negative regulation of action potential

GO:0045776

negative regulation of blood pressure

GO:0045777

positive regulation of blood pressure

GO:0050796

regulation of insulin secretion

GO:0051001

negative regulation of nitric-oxide synthase activity

GO:0051966

regulation of synaptic transmission, glutamatergic

GO:0060135

maternal process involved in female pregnancy

GO:0060259

regulation of feeding behavior

GO:0060405

regulation of penile erection