Gene basic information
| LiverAtlas Gene ID |
HuLG000894 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CNTF |
|
Synonyms |
HCNTF |
|
Gene name |
ciliary neurotrophic factor |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q12.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2169
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005125 |
cytokine activity |
|
GO:0005127 |
ciliary neurotrophic factor receptor binding |
|
GO:0005138 |
interleukin-6 receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005615 |
extracellular space |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0007165 |
signal transduction |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007399 |
nervous system development |
|
GO:0008083 |
growth factor activity |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0030154 |
cell differentiation |
|
GO:0030307 |
positive regulation of cell growth |
|
GO:0030424 |
axon |
|
GO:0032838 |
cell projection cytoplasm |
|
GO:0040007 |
growth |
|
GO:0042517 |
positive regulation of tyrosine phosphorylation of Stat3 protein |
|
GO:0043025 |
neuronal cell body |
|
GO:0043231 |
intracellular membrane-bounded organelle |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0043526 |
neuroprotection |
|
GO:0046427 |
positive regulation of JAK-STAT cascade |
|
GO:0046533 |
negative regulation of photoreceptor cell differentiation |
|
GO:0046668 |
regulation of retinal cell programmed cell death |
|
GO:0046887 |
positive regulation of hormone secretion |
|
GO:0048143 |
astrocyte activation |
|
GO:0048644 |
muscle organ morphogenesis |
|
GO:0048666 |
neuron development |
|
GO:0048680 |
positive regulation of axon regeneration |
|
GO:0051291 |
protein heterooligomerization |
|
GO:0060075 |
regulation of resting membrane potential |
|
GO:0060081 |
membrane hyperpolarization |
|
GO:0070120 |
ciliary neurotrophic factor-mediated signaling pathway |
