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LiverAtlas Gene ID	HuLG000935
Entrez Gene ID	1326
Official Gene Symbol	MAP3K8
Synonyms	COT\|EST\|ESTF\|FLJ10486\|MEKK8\|TPL2\|TplN2\|cNCOT
Gene name	mitogen-activated protein kinase kinase kinase 8
Gene Type	protein-coding
Chromosome	10
Genomics Location	10p11.23
Known cancer genes	Yes
Protein products	Mitogen-activated protein kinase kinase kinase 8 Mitogen-activated protein kinase kinase kinase 8 Mitogen-activated protein kinase kinase kinase 8 Mitogen-activated protein kinase kinase kinase 8 Mitogen-activated protein kinase kinase kinase 8 MAP3K8 protein
Related liver disease name	Intrahepatic cholangiocarcinoma
Database cross reference	HGNC:6860 MIM:191195 Ensembl:ENSG00000107968 HPRD:01863 RefSeq Genomic nucleotide accession:AC_000053 RefSeq Genomic nucleotide gi:89161186

GO ID	GO annotation
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004674	protein serine/threonine kinase activity
GO:0004709	MAP kinase kinase kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0006468	protein phosphorylation
GO:0007049	cell cycle
GO:0007165	signal transduction
GO:0031295	T cell costimulation