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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000969

Entrez Gene ID

1378

Official Gene Symbol

CR1

Synonyms

C3BR|C4BR|CD35|KN

Gene name

complement component (3b/4b) receptor 1 (Knops blood group)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q32

Known cancer genes

Yes

Protein products

Complement receptor type 1

Uncharacterized protein

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

CR1 protein domain SCR25

Complement receptor type 1

Complement receptor type 1

Complement receptor 1

Complement receptor 1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:2334
MIM:120620
Ensembl:ENSG00000203710
HPRD:00398
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002430

complement receptor mediated signaling pathway

GO:0004872

receptor activity

GO:0004875

complement receptor activity

GO:0005887

integral to plasma membrane

GO:0006956

complement activation

GO:0006958

complement activation, classical pathway

GO:0016020

membrane

GO:0045087

innate immune response