Gene basic information
| LiverAtlas Gene ID |
HuLG000976 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ATF2 |
|
Synonyms |
CRENBP1|CREB2|HB16|MGC111558|TREB7 |
|
Gene name |
activating transcription factor 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q32 |
|
Known cancer genes |
Yes |
|
Protein products |
Activating transcription factor 2 splice variant ATF2-var1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:784
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
|
GO:0002224 |
toll-like receptor signaling pathway |
|
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
|
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
|
GO:0003151 |
outflow tract morphogenesis |
|
GO:0003682 |
chromatin binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005624 |
membrane fraction |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005730 |
nucleolus |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0008063 |
Toll signaling pathway |
|
GO:0008270 |
zinc ion binding |
|
GO:0032915 |
positive regulation of transforming growth factor-beta2 production |
|
GO:0034130 |
toll-like receptor 1 signaling pathway |
|
GO:0034134 |
toll-like receptor 2 signaling pathway |
|
GO:0034138 |
toll-like receptor 3 signaling pathway |
|
GO:0034142 |
toll-like receptor 4 signaling pathway |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0045087 |
innate immune response |
|
GO:0045444 |
fat cell differentiation |
|
GO:0046872 |
metal ion binding |
|
GO:0046983 |
protein dimerization activity |
|
GO:0051090 |
regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051403 |
stress-activated MAPK cascade |
|
GO:0060612 |
adipose tissue development |
