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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000987

Entrez Gene ID

1398

Official Gene Symbol

CRK

Synonyms

CRKII

Gene name

v-crk sarcoma virus CT10 oncogene homolog (avian)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.3

Known cancer genes

Yes

Protein products

Adapter molecule crk

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:2362
MIM:164762
Ensembl:ENSG00000167193
HPRD:01267
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000186

activation of MAPKK activity

GO:0005070

SH3/SH2 adaptor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005768

endosome

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0007165

signal transduction

GO:0007596

blood coagulation

GO:0008286

insulin receptor signaling pathway

GO:0030036

actin cytoskeleton organization

GO:0035020

regulation of Rac protein signal transduction

GO:0042169

SH2 domain binding

GO:0045309

protein phosphorylated amino acid binding

GO:0048011

nerve growth factor receptor signaling pathway