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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000990

Entrez Gene ID

1401

Official Gene Symbol

CRP

Synonyms

MGC149895|MGC88244|PTX1

Gene name

C-reactive protein, pentraxin-related

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q21-q23

Known cancer genes

Yes

Protein products

C-reactive protein

C-reactive protein, pentraxin-related

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:2367
MIM:123260
Ensembl:ENSG00000132693
HPRD:00422
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

BodyMap

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005488

binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006953

acute-phase response

GO:0006954

inflammatory response

GO:0006958

complement activation, classical pathway

GO:0008228

opsonization

GO:0010745

negative regulation of macrophage derived foam cell differentiation

GO:0010888

negative regulation of lipid storage

GO:0015485

cholesterol binding

GO:0030169

low-density lipoprotein particle binding

GO:0033265

choline binding

GO:0046872

metal ion binding

GO:0051637

Gram-positive bacterial cell surface binding