Gene basic information
LiverAtlas Gene ID |
HuLG001056 |
Entrez Gene ID |
|
Official Gene Symbol |
CTGF |
Synonyms |
CCN2|HCS24|IGFBP8|MGC102839|NOV2 |
Gene name |
connective tissue growth factor |
Gene Type |
protein-coding |
Chromosome |
6 |
Genomics Location |
6q23.1 |
Known cancer genes |
Yes |
Protein products |
Connective tissue growth factor |
Related liver disease name |
|
Database cross reference |
HGNC:2500
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001502 |
cartilage condensation |
GO:0001503 |
ossification |
GO:0001525 |
angiogenesis |
GO:0001558 |
regulation of cell growth |
GO:0001934 |
positive regulation of protein phosphorylation |
GO:0001968 |
fibronectin binding |
GO:0005178 |
integrin binding |
GO:0005520 |
insulin-like growth factor binding |
GO:0005576 |
extracellular region |
GO:0005578 |
proteinaceous extracellular matrix |
GO:0005615 |
extracellular space |
GO:0005801 |
cis-Golgi network |
GO:0005829 |
cytosol |
GO:0005886 |
plasma membrane |
GO:0005938 |
cell cortex |
GO:0006260 |
DNA replication |
GO:0007155 |
cell adhesion |
GO:0007160 |
cell-matrix adhesion |
GO:0007229 |
integrin-mediated signaling pathway |
GO:0008083 |
growth factor activity |
GO:0008201 |
heparin binding |
GO:0008284 |
positive regulation of cell proliferation |
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
GO:0008544 |
epidermis development |
GO:0009611 |
response to wounding |
GO:0009749 |
response to glucose stimulus |
GO:0010260 |
organ senescence |
GO:0010628 |
positive regulation of gene expression |
GO:0010942 |
positive regulation of cell death |
GO:0014070 |
response to organic cyclic compound |
GO:0016477 |
cell migration |
GO:0030154 |
cell differentiation |
GO:0030324 |
lung development |
GO:0032355 |
response to estradiol stimulus |
GO:0032967 |
positive regulation of collagen biosynthetic process |
GO:0034059 |
response to anoxia |
GO:0043200 |
response to amino acid stimulus |
GO:0043280 |
positive regulation of caspase activity |
GO:0043434 |
response to peptide hormone stimulus |
GO:0044255 |
cellular lipid metabolic process |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0050867 |
positive regulation of cell activation |
GO:0051385 |
response to mineralocorticoid stimulus |
GO:0060401 |
cytosolic calcium ion transport |
GO:0060452 |
positive regulation of cardiac muscle contraction |
GO:0070278 |
extracellular matrix constituent secretion |
GO:0070318 |
positive regulation of G0 to G1 transition |
GO:0070542 |
response to fatty acid |