Gene basic information
| LiverAtlas Gene ID |
HuLG001057 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CTH |
|
Synonyms |
MGC9471 |
|
Gene name |
cystathionase (cystathionine gamma-lyase) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p31.1 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ50357, highly similar to Cystathionine gamma-lyase (EC 4.4.1.1) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2501
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004121 |
cystathionine beta-lyase activity |
|
GO:0004123 |
cystathionine gamma-lyase activity |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0006534 |
cysteine metabolic process |
|
GO:0006749 |
glutathione metabolic process |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0008652 |
cellular amino acid biosynthetic process |
|
GO:0016829 |
lyase activity |
|
GO:0018272 |
protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine |
|
GO:0019344 |
cysteine biosynthetic process |
|
GO:0030170 |
pyridoxal phosphate binding |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0050667 |
homocysteine metabolic process |
|
GO:0051289 |
protein homotetramerization |
|
GO:0070814 |
hydrogen sulfide biosynthetic process |
|
GO:0080146 |
L-cysteine desulfhydrase activity |
