HuLG001058

Entrez Gene ID

1493

Official Gene Symbol

CTLA4

Synonyms

CD|CD152|CELIAC3|CTLAN4|GRD4|GSE|ICOS|IDDM12

Gene name

cytotoxic T-lymphocyte-associated protein 4

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q33

Known cancer genes

Yes

Protein products

Cytotoxic T-lymphocyte protein 4

CTLA-4

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Drug-induced hepatitis

Alcoholic liver cirrhosis

Biliary cirrhosis

Primary biliary cirrhosis

Cross infection of hepatitis virus and HIV

Autoimmune hepatitis

Primary sclerosing cholangitis

Database cross reference

HGNC:2505
MIM:123890
Ensembl:ENSG00000163599
HPRD:00474
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

GO annotation

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0006974

response to DNA damage stimulus

GO:0009897

external side of plasma membrane

GO:0030889

negative regulation of B cell proliferation

GO:0031295

T cell costimulation

GO:0043065

positive regulation of apoptosis

GO:0045334

clathrin-coated endocytic vesicle

GO:0045590

negative regulation of regulatory T cell differentiation

GO:0048471

perinuclear region of cytoplasm

GO:0050853

B cell receptor signaling pathway