Gene basic information
| LiverAtlas Gene ID |
HuLG001063 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CTNNB1 |
|
Synonyms |
CTNNB|DKFZp686D02253|FLJ25606|FLJ37923 |
|
Gene name |
catenin (cadherin-associated protein), beta 1, 88kDa |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2514
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000578 |
embryonic axis specification |
|
GO:0001501 |
skeletal system development |
|
GO:0001569 |
patterning of blood vessels |
|
GO:0001658 |
branching involved in ureteric bud morphogenesis |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001702 |
gastrulation with mouth forming second |
|
GO:0001708 |
cell fate specification |
|
GO:0001711 |
endodermal cell fate commitment |
|
GO:0001837 |
epithelial to mesenchymal transition |
|
GO:0001889 |
liver development |
|
GO:0002053 |
positive regulation of mesenchymal cell proliferation |
|
GO:0002089 |
lens morphogenesis in camera-type eye |
|
GO:0003136 |
negative regulation of heart induction by canonical Wnt receptor signaling pathway |
|
GO:0003337 |
mesenchymal to epithelial transition involved in metanephros morphogenesis |
|
GO:0003338 |
metanephros morphogenesis |
|
GO:0003677 |
DNA binding |
|
GO:0003682 |
chromatin binding |
|
GO:0003690 |
double-stranded DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005198 |
structural molecule activity |
|
GO:0005515 |
protein binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005634 |
nucleus |
|
GO:0005667 |
transcription factor complex |
|
GO:0005737 |
cytoplasm |
|
GO:0005813 |
centrosome |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0005886 |
plasma membrane |
|
GO:0005911 |
cell-cell junction |
|
GO:0005912 |
adherens junction |
|
GO:0005913 |
cell-cell adherens junction |
|
GO:0005915 |
zonula adherens |
|
GO:0005916 |
fascia adherens |
|
GO:0005924 |
cell-substrate adherens junction |
|
GO:0005938 |
cell cortex |
|
GO:0006915 |
apoptosis |
|
GO:0006921 |
cellular component disassembly involved in apoptosis |
|
GO:0007016 |
cytoskeletal anchoring at plasma membrane |
|
GO:0007155 |
cell adhesion |
|
GO:0007160 |
cell-matrix adhesion |
|
GO:0007398 |
ectoderm development |
|
GO:0007403 |
glial cell fate determination |
|
GO:0007494 |
midgut development |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008134 |
transcription factor binding |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009725 |
response to hormone stimulus |
|
GO:0009898 |
internal side of plasma membrane |
|
GO:0009948 |
anterior/posterior axis specification |
|
GO:0009950 |
dorsal/ventral axis specification |
|
GO:0009954 |
proximal/distal pattern formation |
|
GO:0010909 |
positive regulation of heparan sulfate proteoglycan biosynthetic process |
|
GO:0014010 |
Schwann cell proliferation |
|
GO:0016020 |
membrane |
|
GO:0016055 |
Wnt receptor signaling pathway |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0016328 |
lateral plasma membrane |
|
GO:0016331 |
morphogenesis of embryonic epithelium |
|
GO:0016337 |
cell-cell adhesion |
|
GO:0016342 |
catenin complex |
|
GO:0019899 |
enzyme binding |
|
GO:0019900 |
kinase binding |
|
GO:0019901 |
protein kinase binding |
|
GO:0019903 |
protein phosphatase binding |
|
GO:0022009 |
central nervous system vasculogenesis |
|
GO:0030018 |
Z disc |
|
GO:0030027 |
lamellipodium |
|
GO:0030054 |
cell junction |
|
GO:0030057 |
desmosome |
|
GO:0030097 |
hemopoiesis |
|
GO:0030326 |
embryonic limb morphogenesis |
|
GO:0030331 |
estrogen receptor binding |
|
GO:0030521 |
androgen receptor signaling pathway |
|
GO:0030539 |
male genitalia development |
|
GO:0030900 |
forebrain development |
|
GO:0030902 |
hindbrain development |
|
GO:0030997 |
regulation of centriole-centriole cohesion |
|
GO:0031016 |
pancreas development |
|
GO:0031069 |
hair follicle morphogenesis |
|
GO:0031528 |
microvillus membrane |
|
GO:0032331 |
negative regulation of chondrocyte differentiation |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032403 |
protein complex binding |
|
GO:0032993 |
protein-DNA complex |
|
GO:0033077 |
T cell differentiation in thymus |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0034333 |
adherens junction assembly |
|
GO:0034394 |
protein localization at cell surface |
|
GO:0034742 |
APC-Axin-1-beta-catenin complex |
|
GO:0034747 |
Axin-APC-beta-catenin-GSK3B complex |
|
GO:0034750 |
Scrib-APC-beta-catenin complex |
|
GO:0035050 |
embryonic heart tube development |
|
GO:0035112 |
genitalia morphogenesis |
|
GO:0035116 |
embryonic hindlimb morphogenesis |
|
GO:0035117 |
embryonic arm morphogenesis |
|
GO:0035255 |
ionotropic glutamate receptor binding |
|
GO:0035257 |
nuclear hormone receptor binding |
|
GO:0042129 |
regulation of T cell proliferation |
|
GO:0042153 |
RPTP-like protein binding |
|
GO:0042475 |
odontogenesis of dentine-containing tooth |
|
GO:0042493 |
response to drug |
|
GO:0042692 |
muscle cell differentiation |
|
GO:0042733 |
embryonic digit morphogenesis |
|
GO:0043005 |
neuron projection |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043198 |
dendritic shaft |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0043587 |
tongue morphogenesis |
|
GO:0044325 |
ion channel binding |
|
GO:0044334 |
canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition |
|
GO:0044336 |
canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis |
|
GO:0045177 |
apical part of cell |
|
GO:0045202 |
synapse |
|
GO:0045294 |
alpha-catenin binding |
|
GO:0045296 |
cadherin binding |
|
GO:0045445 |
myoblast differentiation |
|
GO:0045453 |
bone resorption |
|
GO:0045603 |
positive regulation of endothelial cell differentiation |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0045671 |
negative regulation of osteoclast differentiation |
|
GO:0045743 |
positive regulation of fibroblast growth factor receptor signaling pathway |
|
GO:0045765 |
regulation of angiogenesis |
|
GO:0045768 |
positive regulation of anti-apoptosis |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046332 |
SMAD binding |
|
GO:0046591 |
embryonic leg joint morphogenesis |
|
GO:0046686 |
response to cadmium ion |
|
GO:0048145 |
regulation of fibroblast proliferation |
|
GO:0048262 |
determination of dorsal/ventral asymmetry |
|
GO:0048469 |
cell maturation |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048489 |
synaptic vesicle transport |
|
GO:0048538 |
thymus development |
|
GO:0048599 |
oocyte development |
|
GO:0048617 |
embryonic foregut morphogenesis |
|
GO:0048660 |
regulation of smooth muscle cell proliferation |
|
GO:0050681 |
androgen receptor binding |
|
GO:0050808 |
synapse organization |
|
GO:0051145 |
smooth muscle cell differentiation |
|
GO:0051149 |
positive regulation of muscle cell differentiation |
|
GO:0051291 |
protein heterooligomerization |
|
GO:0060066 |
oviduct development |
|
GO:0060070 |
canonical Wnt receptor signaling pathway |
|
GO:0060173 |
limb development |
|
GO:0060440 |
trachea formation |
|
GO:0060479 |
lung cell differentiation |
|
GO:0060484 |
lung-associated mesenchyme development |
|
GO:0060492 |
lung induction |
|
GO:0060742 |
epithelial cell differentiation involved in prostate gland development |
|
GO:0060769 |
positive regulation of epithelial cell proliferation involved in prostate gland development |
|
GO:0060789 |
hair follicle placode formation |
|
GO:0060916 |
mesenchymal cell proliferation involved in lung development |
|
GO:0061047 |
positive regulation of branching involved in lung morphogenesis |
|
GO:0061154 |
endothelial tube morphogenesis |
|
GO:0061198 |
fungiform papilla formation |
|
GO:0070369 |
beta-catenin-TCF7L2 complex |
|
GO:0070411 |
I-SMAD binding |
|
GO:0070412 |
R-SMAD binding |
|
GO:0070491 |
repressing transcription factor binding |
|
GO:0070602 |
regulation of centromeric sister chromatid cohesion |
|
GO:0071363 |
cellular response to growth factor stimulus |
|
GO:0071407 |
cellular response to organic cyclic compound |
|
GO:0071681 |
cellular response to indole-3-methanol |
|
GO:0071944 |
cell periphery |
|
GO:0072033 |
renal vesicle formation |
|
GO:0072053 |
renal inner medulla development |
|
GO:0072054 |
renal outer medulla development |
|
GO:0072079 |
nephron tubule formation |
|
GO:0072182 |
regulation of nephron tubule epithelial cell differentiation |
|
GO:0090279 |
regulation of calcium ion import |
|
GO:2000008 |
regulation of protein localization at cell surface |
|
GO:2000017 |
positive regulation of determination of dorsal identity |
