Gene basic information
LiverAtlas Gene ID |
HuLG001110 |
Entrez Gene ID |
|
Official Gene Symbol |
CYP2E1 |
Synonyms |
CPE1|CYP2E|P450NJ|P450C2E |
Gene name |
cytochrome P450, family 2, subfamily E, polypeptide 1 |
Gene Type |
protein-coding |
Chromosome |
10 |
Genomics Location |
10q24.3-qter |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:2631
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0004497 |
monooxygenase activity |
GO:0005783 |
endoplasmic reticulum |
GO:0005789 |
endoplasmic reticulum membrane |
GO:0005792 |
microsome |
GO:0006805 |
xenobiotic metabolic process |
GO:0008202 |
steroid metabolic process |
GO:0009055 |
electron carrier activity |
GO:0016020 |
membrane |
GO:0016098 |
monoterpenoid metabolic process |
GO:0016491 |
oxidoreductase activity |
GO:0016709 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen |
GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
GO:0017144 |
drug metabolic process |
GO:0019825 |
oxygen binding |
GO:0019899 |
enzyme binding |
GO:0020037 |
heme binding |
GO:0046483 |
heterocycle metabolic process |
GO:0046872 |
metal ion binding |
GO:0055114 |
oxidation-reduction process |