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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001110

Entrez Gene ID

1571

Official Gene Symbol

CYP2E1

Synonyms

CPE1|CYP2E|P450NJ|P450C2E

Gene name

cytochrome P450, family 2, subfamily E, polypeptide 1

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24.3-qter

Known cancer genes

Yes

Protein products

Cytochrome P450 2E1

CYP2E1 protein

Putative cytochrome P450 2E1

Cytochrome P450 2E1

Cytochrome P450 2E1

Cytochrome P450IIE1

Cytochrome P450, family 2, subfamily E, polypeptide 1

Cytochrome P450, family 2, subfamily E, polypeptide 1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic hepatitis

Drug-induced hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Alcoholic liver disease

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:2631
MIM:124040
Ensembl:ENSG00000130649
HPRD:11813
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004497

monooxygenase activity

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0006805

xenobiotic metabolic process

GO:0008202

steroid metabolic process

GO:0009055

electron carrier activity

GO:0016020

membrane

GO:0016098

monoterpenoid metabolic process

GO:0016491

oxidoreductase activity

GO:0016709

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

GO:0016712

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

GO:0017144

drug metabolic process

GO:0019825

oxygen binding

GO:0019899

enzyme binding

GO:0020037

heme binding

GO:0046483

heterocycle metabolic process

GO:0046872

metal ion binding

GO:0055114

oxidation-reduction process