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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001128

Entrez Gene ID

1591

Official Gene Symbol

CYP24A1

Synonyms

CP24|CYP24|MGC126273|MGC126274|P450NCC24

Gene name

cytochrome P450, family 24, subfamily A, polypeptide 1

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13

Known cancer genes

Yes

Protein products

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

CYP24A1 protein

Cytochrome P450, family 24, subfamily A, polypeptide 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:2602
MIM:126065
Ensembl:ENSG00000019186
HPRD:00522
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001649

osteoblast differentiation

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0006766

vitamin metabolic process

GO:0006805

xenobiotic metabolic process

GO:0008202

steroid metabolic process

GO:0008403

25-hydroxycholecalciferol-24-hydroxylase activity

GO:0009055

electron carrier activity

GO:0016491

oxidoreductase activity

GO:0016709

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

GO:0020037

heme binding

GO:0030342

1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity

GO:0033280

response to vitamin D

GO:0042359

vitamin D metabolic process

GO:0042369

vitamin D catabolic process

GO:0042446

hormone biosynthetic process

GO:0046872

metal ion binding

GO:0055114

oxidation-reduction process

GO:0070561

vitamin D receptor signaling pathway