Gene basic information
| LiverAtlas Gene ID |
HuLG001130 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CYP27A1 |
|
Synonyms |
CP27|CTX|CYP27 |
|
Gene name |
cytochrome P450, family 27, subfamily A, polypeptide 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q33-qter |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2605
|
Liver relevance
| Liver sepcificity |
Yes/No |
Yes |
|
Evidence |
Translational level from literatures |
|
|
Quality score |
|
|
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005739 |
mitochondrion |
|
GO:0005743 |
mitochondrial inner membrane |
|
GO:0005759 |
mitochondrial matrix |
|
GO:0006699 |
bile acid biosynthetic process |
|
GO:0006805 |
xenobiotic metabolic process |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0008395 |
steroid hydroxylase activity |
|
GO:0009055 |
electron carrier activity |
|
GO:0016020 |
membrane |
|
GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
|
GO:0020037 |
heme binding |
|
GO:0030343 |
vitamin D3 25-hydroxylase activity |
|
GO:0031073 |
cholesterol 26-hydroxylase activity |
|
GO:0046872 |
metal ion binding |
|
GO:0047749 |
cholestanetriol 26-monooxygenase activity |
