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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001132

Entrez Gene ID

1595

Official Gene Symbol

CYP51A1

Synonyms

CP51|CYP51|CYPL1|LDM|P450N14DM|P450L1

Gene name

cytochrome P450, family 51, subfamily A, polypeptide 1

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q21.2

Protein products

Lanosterol 14-alpha demethylase

CYP51A1 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:2649
MIM:601637
Ensembl:ENSG00000001630
HPRD:03381
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

Translational level from literatures

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004497

monooxygenase activity

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0006695

cholesterol biosynthetic process

GO:0006805

xenobiotic metabolic process

GO:0008398

sterol 14-demethylase activity

GO:0009055

electron carrier activity

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO:0020037

heme binding

GO:0046872

metal ion binding