Gene basic information
| LiverAtlas Gene ID |
HuLG001169 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AKR1C1 |
|
Synonyms |
2NALPHANHSD|20NALPHANHSD|C9|DD1|DD1/DD2|DDH|DDH1|HN37|HAKRC|HBAB|MBAB|MGC8954 |
|
Gene name |
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10p15-p14 |
|
Known cancer genes |
Yes |
|
Protein products |
Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1, member C1 (Dihydrodiol dehydrogenase 1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:384
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004033 |
aldo-keto reductase (NADP) activity |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006805 |
xenobiotic metabolic process |
|
GO:0007586 |
digestion |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0015721 |
bile acid and bile salt transport |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0030299 |
intestinal cholesterol absorption |
|
GO:0031406 |
carboxylic acid binding |
|
GO:0032052 |
bile acid binding |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0046683 |
response to organophosphorus |
|
GO:0047006 |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity |
|
GO:0047042 |
androsterone dehydrogenase (B-specific) activity |
|
GO:0047115 |
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity |
|
GO:0047718 |
indanol dehydrogenase activity |
|
GO:0051260 |
protein homooligomerization |
|
GO:0055114 |
oxidation-reduction process |
