Gene basic information
| LiverAtlas Gene ID |
HuLG001171 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
GADD45A |
|
Synonyms |
DDIT1|GADD45 |
|
Gene name |
growth arrest and DNA-damage-inducible, alpha |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p31.2 |
|
Known cancer genes |
Yes |
|
Protein products |
Growth arrest and DNA-damage-inducible 45 alpha Growth arrest and DNA damage-inducible protein GADD45 alpha |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:4095
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000079 |
regulation of cyclin-dependent protein kinase activity |
|
GO:0000086 |
G2/M transition of mitotic cell cycle |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0006281 |
DNA repair |
|
GO:0006469 |
negative regulation of protein kinase activity |
|
GO:0006915 |
apoptosis |
|
GO:0007050 |
cell cycle arrest |
|
GO:0007098 |
centrosome cycle |
|
GO:0042770 |
signal transduction in response to DNA damage |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:0071479 |
cellular response to ionizing radiation |
|
GO:2000379 |
positive regulation of reactive oxygen species metabolic process |
