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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001180

Entrez Gene ID

1659

Official Gene Symbol

DHX8

Synonyms

DDX8|HRH1|PRP22|PRPF22

Gene name

DEAH (Asp-Glu-Ala-His) box polypeptide 8

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q21.31

Known cancer genes

Yes

Protein products

ATP-dependent RNA helicase DHX8

DEAH (Asp-Glu-Ala-His) box polypeptide 8

DEAH (Asp-Glu-Ala-His) box polypeptide 8

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:2749
MIM:600396
Ensembl:ENSG00000067596
HPRD:02672
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000398

nuclear mRNA splicing, via spliceosome

GO:0003723

RNA binding

GO:0004004

ATP-dependent RNA helicase activity

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005681

spliceosomal complex

GO:0006396

RNA processing

GO:0008380

RNA splicing

GO:0016787

hydrolase activity

GO:0071013

catalytic step 2 spliceosome