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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001183

Entrez Gene ID

1663

Official Gene Symbol

DDX11

Synonyms

CHL1|CHLR1|KRG2|MGC133249|MGC9335

Gene name

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p11

Known cancer genes

Yes

Protein products

Probable ATP-dependent RNA helicase DDX11

DDX11 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:2736
MIM:601150
Ensembl:ENSG00000013573
HPRD:03095
RefSeq Genomic nucleotide accession:AC_000144
RefSeq Genomic nucleotide gi:157704453

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000070

mitotic sister chromatid segregation

GO:0000084

S phase of mitotic cell cycle

GO:0000086

G2/M transition of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000790

nuclear chromatin

GO:0000922

spindle pole

GO:0003677

DNA binding

GO:0003678

DNA helicase activity

GO:0003723

RNA binding

GO:0004003

ATP-dependent DNA helicase activity

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO:0007049

cell cycle

GO:0007062

sister chromatid cohesion

GO:0008094

DNA-dependent ATPase activity

GO:0008284

positive regulation of cell proliferation

GO:0016818

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO:0030496

midbody

GO:0044419

interspecies interaction between organisms